The Southern Center of Environmental Management Administration collaborates with counties and cities to establish a "Regional Governance Platform for Cloud-based Intelligent Inspection and Early Warning System of Air Pollution in the Southern Region" for air pollution control based on two main pillars "Routine Control" and "Air Pollution Response". For "Routine Control", we combine intelligent and systematic analysis of air pollution data such as stack's smoke images, air pollution Internet of Things, and air pollution operating parameters. The real-time early warning is effectively adopted and potential high-pollution hot spots are obtained. For "Air Pollution Response", we utilize air pollution forecasting models, air pollution web, and air pollutant monitoring data to predict future hotspots of air pollution deterioration, so as to strengthen air pollution response in hotspots and initiate air pollution reduction in up-wind counties and cities in advance.